Are some of your pregnant patients taking Wellbutrin? If so, it could be a danger to them and their baby. This drug is extremely popular, but it has a serious history. Wellbutrin promised to make patients "happy, horny and skinny," plus they might even quit smoking. GlaxoSmithKline's sales department promised physicians the pills would sell. But then came the side effects, including strokes and much more.1
Wellbutrin is an antidepressant. It is used to treat depression including seasonal depression, otherwise known as SAD (Seasonal Affective Disorder), the blues that may occur in the fall and winter. Scientists claim Wellbutrin should work by increasing certain types of brain activity.
The drug is also used to treat attention deficit hyperactivity disorder, ADHD (a longtime suspect diagnosis); difficulty focusing or controlling actions; antidepressive disorder; or episodes of other abnormal moods. My favorite diagnosis: "remaining [more] still or quiet than other people who are the same age."2 We used to call those good kids. Now we have a pill for them.
For those who like to dabble with more exotic issues, the literature reports that Wellbutrin is used for popular off-label uses such as getting high, weight loss, bipolar depression, RLS (restless leg syndrome), pathological gambling and sexual dysfunction. The FDA does not approve Wellbutrin for any of these conditions. Restless leg syndrome – really?
Side Effects: Some Moderate, Some Severe ... Some Deadly?
When given to women who are suffering from pregnancy depression or postpartum depression, Wellbutrin may increase the risk of serious birth defects including heart defects (left outflow heart defect), bilateral club feet, and reduced testicles for male babies. It may also interfere with fetal growth. Depressingly, the Mayo Clinic still recommends Wellbutrin for depression during pregnancy.
Stark problems created when pregnant women take antidepressants are internationally recognized. Regulatory agencies from several countries are warning that antidepressants may induce birth defects including heart and lung malfunction, preterm births and numerous other physical defects.
But what has made Wellbutrin infamous is the initial large number of seizures reported; so many that Wellbutrin was initially withdrawn from the market.3 And that's not to mention the "moderate" and serious side effects from the drug,2 which according to the National Institutes of Health include:
Moderate Side Effects
Serious Side Effects
Oh, and by the way, suicide can also be a problem. The FDA requires all antidepressants to carry a "black box" warning stating that antidepressants may increase suicide risk in individuals younger than age 25.4 (With all the side effects, I might suggest that slow, lingering, painful death is an additional possibility.)
Big Pharma Warnings
GlaxoSmithKline is quick to tell you on its website that Wellbutrin is not for everyone. GSK admits a risk of seizure. It suggests that you should not take Wellbutrin with alcohol or sedatives, or monoamine oxidase inhibitors (MAOIs) or certain other medications, or with a nicotine patch, or if you have liver or kidney problems.
Reassuringly GSK informs us that Wellbutrin "is approved only for adults 18 years and over." However, "in some children, teens, and young adults, antidepressants increase suicidal thoughts or actions."
A Little History of Wellbutrin, Including Fraud and Bribery
Bupropion was invented by scientist Nariman Mehta in 1969.5 It was then approved by the U.S. Food and Drug Administration (FDA) as an antidepressant on December 1985 and marketed under the name Wellbutrin. Increased incidence of seizures, however, caused the withdrawal of the drug in 1986. Wellbutrin was re-introduced to the market in 1989.
In 2012, the U.S. Justice Department announced that GlaxoSmithKline had agreed to plead guilty and pay a $3 billion fine, in part for promoting the unapproved use of Wellbutrin for weight loss and sexual dysfunction.6 GSK also was charged by the federal government for paying kickbacks to doctors and misrepresenting its products to the public. GSK secretly employed media physiologist and sex advice guru, Dr. Drew Pinsky, with his popular "Loveline" show. Dr. Drew was paid some $275,000 to promote the drugs, without informing anyone he was paid. One of the key drugs involved in the scandal was Wellbutrin.7
Talk to Your Patients
Wellbutrin has made GSK rich and continues to do so today. Naturally, there are many lawsuits pending against the manufacturer – but the (monetary) benefits for GSK certainly outweigh the costs. If you know a patient is taking Wellbutrin, particularly if they are pregnant, you might suggest they get a second opinion from an MD you trust. If the patient is already suffering side effects from the use of Wellbutrin, legal counseling also may be appropriate.
References
When sports chiropractors first appeared at the Olympic Games in the 1980s, it was alongside individual athletes who had experienced the benefits of chiropractic care in their training and recovery processes at home. Fast forward to Paris 2024, where chiropractic care was available in the polyclinic for all athletes, and the attitude has now evolved to recognize that “every athlete deserves access to sports chiropractic."
It is estimated that 61% of patients with CTS avoid taking surgical options due to postoperative complications and costly surgical procedures. Chiropractic care offers a comprehensive and effective treatment for carpal tunnel syndrome, addressing the condition from multiple angles. Recent studies also have unveiled a game-changing adjunct to chiropractic treatments for CTS: nerve flossing.
Some doctors thrive in a personality-based clinic and have a loyal following no matter what services or equipment they offer, but for most chiropractic offices who are trying to grow and expand, new equipment purchases help us stay relevant and continue to service our client base in the best, most up-to-date manner possible. So, regarding equipment purchasing: should you lease, get a bank loan, or pay cash?
