While cervical disc pathology can unquestionably produce radiculopathy, many patients presenting with arm pain, paresthesia or perceived weakness do not exhibit the clinical behavior of true nerve-root compromise. In these cases, failure to differentiate the primary pain generator may lead to unnecessary spinal injections, nerve ablation procedures or surgical consultation despite limited likelihood of benefit.
"No Benefit from Amoxicillan"
A randomized double blind clinical trial of children ages 3-6 recently released from the Agency for Health Care Policy and Research (AHCPR), concluded that "there was no benefit from amoxicillan prophylaxis compared to a placebo control in preventing new AOM (acute otitis media) episodes."
Free of AOM (%)
30-90 Days:
Placebo Group:71% Otitis Free
Daily Amoxicillan Group: 65% Otitis Free
Twice Daily Amoxicillan Group: 62% Otitis Free
3 Months or Longer:
Placebo Group:54% Otitis Free
Daily Amoxicillan Group: 63% Otitis Free
Twice Daily Amoxicillan Group: 60% Otitis Free
SOURCE: Berman S. Continuous twice daily or once daily amoxicillan prophylaxis compared to placebo for children with recurrent otitis media. Agency for Health Care Policy and Research grant no.: RO3 HS07283-02.